tissue-factor-pathway inhibitor 2

glycoprotein containing 20% carbohydrate which moves as a beta(1) globulin on electrophoresis; MW 36,000; TFPI-2 is an important regulator of the extrinsic pathway of blood coagulation; a factor VIIA antagonist; present in placenta, maternal serum in late pregnancy, liver, heart, pancreas, and other tissues; a serine protease inhibitor; GenBank L27624 (human); REfSeq NM_006528 (human), NM_009364 (mouse)

Also Known As:

PP5; MSPI protein; PP5 protein, human; PP5 protein, mouse; Placental protein 5, human; TFPI-2; TFPI2 protein, human; Tfpi2 protein, mouse; matrix-associated serine protease inhibitor; placenta-specific protein 5; placental protein 5; tissue factor pathway inhibitor 2 protein, human; tissue factor pathway inhibitor 2 protein, mouse; tissue factory pathway inhibitor-2

Pharmalogical Action Categories:

D015842 - Serine Proteinase Inhibitors

Carbohydrates: 22023
- Glycoconjugates: 1353
  - Glycoproteins: 24834
    - tissue-factor-pathway inhibitor 2: 294
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Glycoproteins: 24834
    - tissue-factor-pathway inhibitor 2: 294

K Hozumi Selected Research

K Hozumi Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure